ea0049ep704 | Obesity | ECE2017
Letra Liliana
, Rodrigues Tiago
, Matafome Paulo
, Duro Diana
, Lemos Raquel
, Patricio Miguel
, Castelo-Branco Miguel
, Baldeiras Ines
, Seica Raquel
, Santana Isabel
Background: Several studies have highlighted the contribution of adipose tissue dysfunction to the development and progression of Alzheimers Disease (AD), which may depend on alterations in adipokine secretion. Leptin and adiponectin are the most abundant adipokines in circulation, with recognized systemic effects, but also able to cross the blood-brain barrier and influence cognitive-related structures, such as the hippocampus.Objective: To determ...